Alex `Sandy’ Pentland directs MIT’s Human Dynamics Laboratory and the MIT Media Lab Entrepreneurship Program, co-leads the World Economic Forum Big Data and Personal Data initiatives, and is a founding member of the Advisory Boards for Nissan, Motorola Mobility, Telefonica, and a variety of start-up firms. He has previously helped create and direct MIT’s Media Laboratory, the Media Lab Asia laboratories at the Indian Institutes of Technology, and Strong Hospital’s Center for Future Health.

In 2012 Forbes named Sandy one of the ‘seven most powerful data scientists in the world’, along with Google founders and the CTO of the United States, and in 2013 he won the McKinsey Award from Harvard Business Review. He is among the most-cited computational scientists in the world, and a pioneer in computational social science, organizational engineering, wearable computing (Google Glass), image understanding, and modern biometrics. His research has been featured in Nature, Science, and Harvard Business Review, as well as being the focus of TV features on BBC World, Discover and Science channels. His most recent book is `Social Physics: How Good Ideas Spread–The Lessons from a New Science,’ published by The Penguin Press.

Over the years Sandy has advised more than 50 PhD students. Almost half are now tenured faculty at leading institutions, with another one-quarter leading industry research groups and a final quarter founders of their own companies.

Sandy’s research group and entrepreneurship program have spun off more than 30 companies to date, three of which are publicly listed and several that serve millions of poor in Africa and South Asia. Recent spin-offs have been featured in publications such as the Economist and the New York Times, as well as winning a variety of prizes from international development organizations.

Pentland, A. (2014) Social Physics, Penguin Press NY NY

Pickard, G., Pan, W., Rahwan, I., Cebrian, M.,Crane, R., Madan, A., Pentland, A., `Time-

Critical Social Mobilization.’ Science 28: Vol. 334 no. 6055 pp. 509-512, (2011)

Woolley, A.W., Chabris, C.F., Pentland, A., Hashmi, N., & Malone, T.W. Evidence for a Collective Intelligence Factor in the Performance of Human Groups, Sept. 30, 2010 Science, Vol. 330 no. 6004 pp. 686-68

Pentland, A., (2010) To Signal Is Human, American Scientist, Vol. 98, pp. 204-210

Eagle, N., Pentland, A., and Lazer, D. (2009), “Inferring Social Network Structure using Mobile Phone Data”, Proceedings of the National Academy of Sciences

Pentland, A., (2008) Honest Signals: how they shape our world, MIT Press, Cambridge, MA

Pentland,A., (2007) “Automatic Mapping and Modeling of Human Networks,” Physica A: Statistical Mechanics and Its Applications 378 (1): 59-67.

Sung, M., Marci, C., Pentland, A., (2005) Wearable feedback systems for rehabilitation, Journal of Neuroengineering and Rehabilitation, 2:2-17

Pentland, A., (2005) Socially Aware Computation and Communication, IEEE Computer, March 2005, pp. 63-70

Pentland, A., (2004) HealthWear: Medical Technology Becomes Wearable (2004) IEEE Computer, May, 2004, 37(5), pp. 42-49

Kumar VS, Wentzell KJ, Mikkelsen T, Pentland A, Laffel LM. (2004) The DAILY (Daily Automated Intensive Log for Youth) Trial: A Wireless, Portable System to Improve Adherence and Glycemic Control in Youth with Diabetes. Diabetes Technology and Therapy. 2004 Aug;6(4):445-53.

Roy, D., and Pentland, A., (2002) Learning words from sights and sounds: A computational model, Cognitive Science, 26 113-146.

Weng, J., McClelland, J., Pentland, A., Sporns, O., Stockman, I., Sur, M., Thelen, E., (2001) Automonous Mental Development by Robots and Animals, Science, V291 No. 5504, Jan 26, 2001

Pentland, A., (2000) Looking at People: Sensing for Ubiquitous and Wearable Computing IEEE Transactions on Pattern Analysis and Machine Intelligence, 22(1), pp. 107-119, Jan. 2000.

Oliver, N., Rosario, B., and Pentland, A., (2000) A Bayesian Computer Vision System for Modeling Human Interaction, IEEE Transactions on Pattern Analysis and Machine Intelligence, 22(8), pp. 831-843

Pentland, A., and Liu, A., (1999) Modeling and Prediction of Human Behavior, Neural Computation, 11(1), pp. 229-242, Jan 1999 Pentland, A., (1998) Wearable Intelligence, Scientific American, Special Issue on Intelligence, pp. 90-95

Starner, T., and Pentland, A., (1998) Real-Time American Sign Language Recognition from Video Using Hidden Markov Models, IEEE Transactions on Pattern Analysis and Machine Vision, Nov. 1998.

Essa, I., Pentland, A., (1997), Coding, Analysis, Interpretation and Recognition of Facial Expressions, IEEE Trans. Pattern Analysis and Machine Vision}, Vol. 19, No. 7, pp. 757-763

Pentland, A. (1996) Smart Rooms, Smart Clothes, Scientific American, Vol. 274, No. 4, pp. 68-76, April 1996.

Takeo Kanade is the U. A. and Helen Whitaker University Professor of Computer Science and Robotics. He received his Doctoral degree in Electrical Engineering from Kyoto University, Japan, in 1974. After holding a faculty position in the Department of Information Science, Kyoto University, he joined Carnegie Mellon University in 1980. He was the Director of the Robotics Institute from 1992 to 2001, and a founding Director of Quality of Life Technology Research Center from 2006 to 2012. In Japan, he founded the Digital Human Research Center in Tokyo and served as the founding director from 2001 to 2010.

Dr. Kanade works in multiple areas of robotics: computer vision, multi-media, manipulators, autonomous mobile robots, medical robotics and sensors. He has written more than 300 technical papers and reports in these areas, and holds more than 20 patents. He has been the principal investigator of more than a dozen major vision and robotics projects at Carnegie Mellon.

Dr. Kanade has been elected to the National Academy of Engineering, and also to the American Academy of Arts and Sciences. He is a Fellow of the IEEE, a Fellow of the ACM, a Founding Fellow of American Association of Artificial Intelligence (AAAI), and the former and founding editor of International Journal of Computer Vision.

The awards he received include the Franklin Institute Bower Prize, Okawa Award, C&C Award, ACM/AAAI Allen Newell Award, Joseph Engelberger Award, IEEE Robotics and Automation Society Pioneer Award, FIT Accomplishment Award, and IEEE PAMI-TC Azriel Rosenfeld Lifetime Accomplishment Award.

金出武雄　”独創はひらめかない―「素人発想、玄人実行」の法則”, 日本経済新聞出版社, 2012年11月.

Takeo Kanade and Martial Hebert, “First-Person Vision,” Proceedings of the IEEE, Special Issue on Quality of Life Technology, Vol. 100, No. 8, p. 2442, August 2012.

Seungil Huh, Elmer Daifei Ker, Ryoma Bise, Mei Chen and Takeo Kanade, “Automated Mitosis Detection of Stem Cell Populations in Phase-Contrast Microscopy Images,” IEEE Transactions on Medical Imaging, Vol.30, No. 3: pp586-96. March 2011.

Yan Li, Leon Gu and Takeo Kanade, “Robustly Aligning a Shape Model and Its Application to Car Alignment of Unknown Pose,” IEEE Transactions on Pattern Analysis and Machine Intelligence, September 2011 (vol. 33 no. 9),pp. 1860-1876.

Kang Li, Mei Chen, Takeo Kanade, Eric Miller, Lee Weiss, and Phil Campbell, “Cell Population Tracking and Lineage Construction with Spatiotemporal Context,” Medical Image Analysis, Vol. 12, , No. 5, October, 2008, pp. 546 – 566.

Takeo Kanade and P. J. Narayanan, “Virtualized Reality: Perspectives on 4D Digitization of Dynamic Events”, IEEE Computer Graphics and Applications, Vol. 27, No. 3, May/June 2007:32-40.

H. Schneiderman and T. Kanade, “Object Detection Using the Statistics of Parts,” International Journal of Computer Vision, Vol. 56 No. 3, February/March 2004: 151-177.

Y. Tian, T. Kanade, and J. Cohn, “Recognizing action units for facial expression analysis”, IEEE Transactions on Pattern Analysis and Machine Intelligence, Vol. 23, No. 2, February 2001, pp. 97 – 115.

V. Brajovic and T. Kanade, “A VLSI Sorting Image Sensor: Global Massively Intensity-to-Time Processing for Low-Latency, Adaptive Vision,” IEEE Trans. Robotics and Automation, Vol. 15, No. 1, pp. 67-75, February 1999.

C. Tomasi and T. Kanade, “Shape and Motion from Image Streams Under Orthography: A Factorization Method,” International Journal of Computer Vision, Vol. 9, No. 2, pp. 137-154, November 1992.

T. Kanade, “Recovery of the 3-Dimensional Shape of an Object from Its Single View,” Artificial Intelligence, Vol. 17, pp. 409-460, November 1981.

T. Kanade, “A Theory of Origami World,” Artificial Intelligence, Vol. 13, pp. 279-311, June 1980.

Yann LeCun is Director of AI Research at Facebook, and Silver Professor of Data Science, Computer Science, Neural Science, and Electrical Engineering at New York University, affiliated with the NYU Center for Data Science, the Courant Institute of Mathematical Science, the Center for Neural Science, and the Electrical and Computer Engineering Department.

He received the Electrical Engineer Diploma from Ecole Supérieure d’Ingénieurs en Electrotechnique et Electronique (ESIEE), Paris in 1983, and a PhD in Computer Science from Université Pierre et Marie Curie (Paris) in 1987. After a postdoc at the University of Toronto, he joined AT&T Bell Laboratories in Holmdel, NJ in 1988. He became head of the Image Processing Research Department at AT&T Labs-Research in 1996, and joined NYU as a professor in 2003, after a brief period as a Fellow of the NEC Research Institute in Princeton. From 2012 to 2014 he directed NYU’s initiative in data science and became the founding director of the NYU Center for Data Science. He was named Director of AI Research at Facebook in late 2013 and retains a part-time position on the NYU faculty.

His current interests include AI, machine learning, computer perception, mobile robotics, and computational neuroscience. He has published over 180 technical papers and book chapters on these topics as well as on neural networks, handwriting recognition, image processing and compression, and on dedicated circuits and architectures for computer perception. The character recognition technology he developed at Bell Labs is used by several banks around the world to read checks and was reading between 10 and 20% of all the checks in the US in the early 2000s. His image compression technology, called DjVu, is used by hundreds of web sites and publishers and millions of users to access scanned documents on the Web. Since the mid 1980’s he has been working on deep learning methods, particularly the convolutional network model, which is the basis of many products and services deployed by companies such as Facebook, Google, Microsoft, Baidu, IBM, NEC, AT&T and others for image and video understanding, document recognition, human-computer interaction, and speech recognition.

LeCun has been on the editorial board of IJCV, IEEE PAMI, and IEEE Trans. Neural Networks, was program chair of CVPR’06, and is chair of ICLR 2013 and 2014. He is on the science advisory board of Institute for Pure and Applied Mathematics, and Neural Computation and Adaptive Perception Program of the Canadian Institute for Advanced Research. He has advised many large and small companies about machine learning technology, including several startups he co-founded. He is the lead faculty at NYU for the Moore-Sloan Data Science Environment, a $36M initiative in collaboration with UC Berkeley and University of Washington to develop data-driven methods in the sciences. He is the recipient of the 2014 IEEE Neural Network Pioneer Award.

IEEE Neural Network Pioneer Award, 2014

Y. LeCun, L. Bottou, Y. Bengio and P. Haffner: Gradient-Based Learning Applied to Document Recognition, Proceedings of the IEEE, 86(11):2278-2324, November 1998

Yoshua Bengio and Yann LeCun: Scaling learning algorithms towards AI, in Bottou, L. and Chapelle, O. and DeCoste D. and Weston, J. (Eds), Large-Scale Kernel Machines, MIT Press, 2007, \cite{bengio-lecun-07}

Yann LeCun, Sumit Chopra, Raia Hadsell, Marc’Aurelio Ranzato and Fu-Jie Huang: A Tutorial on Energy-Based Learning, in Bakir, G. and Hofman, T. and Schölkopf, B. and Smola, A. and Taskar, B. (Eds), Predicting Structured Data, MIT Press, 2006

Y. LeCun, B. Boser, J. S. Denker, D. Henderson, R. E. Howard, W. Hubbard and L. D. Jackel: Backpropagation Applied to Handwritten Zip Code Recognition, Neural Computation, 1(4):541-551, Winter 1989

Pierre Sermanet, David Eigen, Xiang Zhang, Michael Mathieu, Rob Fergus and Yann LeCun: OverFeat: Integrated Recognition, Localization and Detection using Convolutional Networks, International Conference on Learning Representations (ICLR2014), CBLS, (OpenReview), (Arxiv:1312.6229), April 2014

Clement Farabet, Camille Couprie, Laurent Najman and Yann LeCun: Learning Hierarchical Features for Scene Labeling, IEEE Transactions on Pattern Analysis and Machine Intelligence, August 2013,

Yann LeCun: Learning Invariant Feature Hierarchies, in Fusiello, Andrea and Murino, Vittorio and Cucchiara, Rita (Eds), European Conference on Computer Vision (ECCV 2012), 7583:496-505, Lecture Notes in Computer Science Springer, ISBN:978-3-642-33862-5, Workshop on Biological and Computer Vision Interfaces (invited paper), 2012

Clement Farabet, Rafael Paz, Jose Perez-Carrasco, Carlos Zamarreno, Alejandro Linares-Barranco, Yann LeCun, Eugenio Culurciello, Teresa Serrano-Gotarredona and Bernabe Linares-Barranco: Comparison Between Frame-Constrained Fix-Pixel-Value and Frame-Free Spiking-Dynamic-Pixel ConvNets for Visual Processing, Frontiers in Neuroscience, 6(00032), DOI: 10.3389/fnins.2012.00032 (open access), 2012

Clement Farabet, Yann LeCun, Koray Kavukcuoglu, Eugenio Culurciello, Berin Martini, Polina Akselrod and Selcuk Talay: Large-Scale FPGA-based Convolutional Networks, in Bekkerman, Ron and Bilenko, Mikhail and Langford, John (Eds), Scaling up Machine Learning: Parallel and Distributed Approaches, Cambridge University Press, 2011

Koray Kavukcuoglu, Pierre Sermanet, Y-Lan Boureau, Karol Gregor, Michaël Mathieu and Yann LeCun: Learning Convolutional Feature Hierachies for Visual Recognition, Advances in Neural Information Processing Systems (NIPS 2010), 23, 2010

Koray Kavukcuoglu, Marc’Aurelio Ranzato, Rob Fergus and Yann LeCun: Learning Invariant Features through Topographic Filter Maps, Proc. International Conference on Computer Vision and Pattern Recognition (CVPR’09), IEEE, 2009

Raia Hadsell, Pierre Sermanet, Marco Scoffier, Ayse Erkan, Koray Kavackuoglu, Urs Muller and Yann LeCun: Learning Long-Range Vision for Autonomous Off-Road Driving, Journal of Field Robotics, 26(2):120-144, February 2009

Marc’Aurelio Ranzato, Y-Lan Boureau and Yann LeCun: Sparse feature learning for deep belief networks, Advances in Neural Information Processing Systems (NIPS 2007), 20, 2007

M. Osadchy, Y. LeCun and M. Miller: Synergistic Face Detection and Pose Estimation with Energy-Based Models, Journal of Machine Learning Research, 8:1197-1215, May 2007

Tatsuya Kawahara received B.E. in 1987, M.E. in 1989, and Ph.D. in 1995, all in information science, from Kyoto University, Kyoto, Japan.

In 1990, he became a Research Associate in the Department of Information Science, Kyoto University. From 1995 to 1996, he was a Visiting Researcher at Bell Laboratories, Murray Hill, NJ, USA. Currently, he is a Professor in the Academic Center for Computing and Media Studies and an Affiliated Professor in the School of Informatics, Kyoto University.

He has also been an Invited Researcher at ATR and NICT.
He has been conducting several speech-related projects in Japan including free large vocabulary continuous speech recognition software (http://julius.sourceforge.jp/) and the automatic transcription system for the Japanese Parliament (Diet).

From 2003 to 2006, he was a member of IEEE SPS Speech Technical Committee.
He was a general chair of IEEE Automatic Speech Recognition & Understanding workshop (ASRU 2007). He also served as a Tutorial Chair of INTERSPEECH 2010 and a Local Arrangement Chair of ICASSP 2012.

He is an editorial board member of Elsevier Journal of Computer Speech and Language and APSIPA Transactions on Signal and Information. He is VP-Publications (BoG member) of APSIPA and a senior member of IEEE.

2000 IPSJ Sakai Special Researcher Award

2011 IPSJ Kiyasu Special Industrial Achievement Award

2012 IPSJ Best Paper Award

2012 DOCOMO Mobile Science Award

2012 The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology

●Spontaneous Speech Recognition
T. Kawahara. Transcription system using automatic speech recognition for the Japanese Parliament (Diet). In Proc. AAAI/IAAI, pp.2224–2228, 2012.

Y. Akita and T. Kawahara. Statistical transformation of language and pronunciation models for spontaneous speech recognition. IEEE Trans. Audio, Speech \& Language Process., Vol.18, No.6, pp.1539–1549, 2010.

●Indexing and Annotation of Lectures & Meetings
G. Neubig, Y. Akita, S.Mori, and T. Kawahara. A monotonic statistical machine translation approach to speaking style transformation. Computer Speech and Language, Vol.26, No.5, pp.349–370, 2012.

T. Kawahara, M. Hasegawa, K. Shitaoka, T. Kitade, and H. Nanjo. Automatic indexing of lecture presentations using unsupervised learning of presumed discourse markers. IEEE Trans. Speech \& Audio Process., Vol.12, No.4, pp. 409–419, 2004.

M. Nishida and T.Kawahara. Speaker model selection based on Bayesian information criterion applied to unsupervised speaker indexing. IEEE Trans. Speech \& Audio Process., Vol.13, No.4, pp. 583–592, 2005.

●Speech Understanding
I. R.Lane, T. Kawahara, T. Matsui, and S. Nakamura. Out-of-domain utterance detection using classification confidences of multiple topics. IEEE Trans. Audio, Speech \& Language Process., Vol.15, No.1, pp.150–161, 2007.

H. Nanjo and T. Kawahara. A new ASR evaluation measure and minimum Bayes-risk decoding for open-domain speech understanding. In Proc. IEEE-ICASSP, Vol.1, pp.1053–1056, 2005.

T. Kawahara, C.-H. Lee, and B.-H. Juang. Flexible speech understanding based on combined key-phrase detection and verification. IEEE Trans. Speech \& Audio Process., Vol.6, No.6, pp. 558–568, 1998.)

●Spoken Dialogue Systems
T. Misu and T. Kawahara. Bayes risk-based dialogue management for document retrieval system with speech interface. Speech Communication, Vol.52, No.1, pp.61–71, 2010.

T. Misu and T. Kawahara. Dialogue strategy to clarify user’s queries for document retrieval system with speech interface. Speech Communication, Vol.48, No.9, pp.1137–1150, 2006.

K. Komatani, S. Ueno, T. Kawahara, and H. G. Okuno. User modeling in spoken dialogue systems to generate flexible guidance. User Modeling and User-Adapted Interaction, Vol.15, No.1, pp. 169–183, 2005.

●Robust Speech Processing
D. Cournapeau, S. Watanabe, A. Nakamura, and T. Kawahara. Online unsupervised classification with model comparison in the Variational Bayes framework for voice activity detection. IEEE J. Selected Topics in Signal Processing, Vol.4, No.6, pp.1071–1083, 2010.

R. Gomez and T. Kawahara. Robust speech recognition based on dereverberation parameter optimization using acoustic model likelihood. IEEE Trans. Audio, Speech \& Language Process., Vol.18, No.7, pp.1708–1716, 2010.

Y. Kida and T. Kawahara. Evaluation of voice activity detection by combining multiple features with weight adaptation. In Proc. INTERSPEECH, pp.1966–1969, 2006.

●CALL (Computer Assisted Language Learning)
T. Kawahara and N. Minematsu. Computer-Assisted Language Learning (CALL) Systems. Tutorial at InterSpeech 2012.

H. Wang, C. J. Waple, and T. Kawahara. Computer assisted language learning system based on dynamic question generation and error prediction for automatic speech recognition. Speech Communication, Vol.51, No.10, pp.995–1005, 2009.

Y. Tsubota, T. Kawahara, and M. Dantsuji. An English pronunciation learning system for Japanese students based on diagnosis of critical pronunciation errors. ReCALL Journal, Vol.16, No.1, pp.173–188, 2004.

●Large Vocabulary Continuous Speech Recognition Platform
A. Lee and T. Kawahara. Recent development of open-source speech recognition engine Julius. In Proc. APSIPA ASC, pp.131–137, 2009.

T. Kawahara, A. Lee, K. Takeda, K. Itou, and K. Shikano. Recent progress of open-source LVCSR engine Julius and Japanese model repository. In Proc. ICSLP, pp.3069–3072, 2004.

A. Lee, T. Kawahara, and K. Shikano. Julius — an open source real-time large vocabulary recognition engine. In Proc. EUROSPEECH, pp.1691–1694, 2001.

●Multi-modal Conversation Analysis
T. Kawahara. Multi-modal sensing and analysis of poster conversations toward smart posterboard. In Proc. SIGdial Meeting Discourse \& Dialogue, pp.1–9 (keynote speech), 2012.

*Grand Challenge Special Prize on the Best Application of a Theoretical Framework from the 19th Annual ACM International Conference on Multimedia (30th November, 2011) shared with Y. Ushiku and Y. Kuniyoshi

*Best Paper Award from the Robotics Society of Japan (16th September, 2009) shared with T. Sato, H. Kubodera, and T. Mori

*The first place in the fine-grained classification task, and take second place in the classification task at ImageNet Large Scale Visual Recognition Challenge 2012 (12th October, 2012) shared with N. Gunji, T. Higuchi, K. Yasumoto, H. Muraoka, Y. Ushiku, and Y. Kuniyoshi

(1)　Hiroharu Kato, Tatsuya Harada. Image Reconstruction from Bag-of-Visual-Words. In The Twenty-Seventh IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR 2014), accepted, 2014.

(2)　Yoshitaka Ushiku, Tatsuya Harada. Three Guidelines of Online Learning for Large-Scale Visual Recognition. In The Twenty-Seventh IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR 2014), accepted, 2014.

(3)　Tatsuya Harada, and Yasuo Kuniyoshi. Graphical Gaussian Vector for Image Categorization. the Twenty-Sixth Annual Conference on Neural Information Processing Systems (NIPS 2012), pp.1556-1564, 2012.

(4)　Yoshitaka Ushiku, Tatsuya Harada, and Yasuo Kuniyoshi. Efficient Image Annotation for Automatic Sentence Generation. the 20th Annual ACM International Conference on Multimedia (ACM MM 2012), pp.549-558, 2012.

(5)　Yuya Yamashita, Tatsuya Harada, and Yasuo Kuniyoshi. Causal Flow. IEEE Transactions on Multimedia, Vol.3, No.3, pp.619-629, 2012.

(6)　Takashi Shibuya, Tatsuya Harada, and Yasuo Kuniyoshi. Reliable index for measuring information flow. Phys. Rev. E 84, 061109 (2011)

(7)　Tatsuya Harada, Yoshitaka Ushiku, Yuya Yamashita, and Yasuo Kuniyoshi. Discriminative Spatial Pyramid. In The Twenty-Forth IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR 2011), pp.1617-1624, 2011.

(8)　Tatsuya Harada, Hideki Nakayama, and Yasuo Kuniyoshi. Improving Local Descriptors by Embedding Global and Local Spatial Information. In The 11th European Conference on Computer Vision (ECCV 2010), 2010.

(9)　Hideki Nakayama, Tatsuya Harada, and Yasuo Kuniyoshi. Global Gaussian Approach for Scene Categorization Using Information Geometry. In The Twenty-Third IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR 2010), 2010.

(10)　Takashi Shibuya, Tatsuya Harada, and Yasuo Kuniyoshi. Causality Quantification and its Applications: Structuring and Modeling of Multivariate Time Series. Proc. of the 15th ACM SIGKDD International Conference on Knowledge Discovery and Data Mining (KDD 2009), pp.787-795, 2009.

(11)　Rie Matsumoto, Hideki Nakayama, Tatsuya Harada and Yasuo Kuniyoshi. Journalist Robot: Robot System Making News Articles from Real World. IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS 2007), pp.1234-1241, 2007.

Hiroshi Ishiguro received a D. Eng. in systems engineering from the Osaka University, Japan in 1991. He is currently Professor of Department of Systems Innovation in the Graduate School of Engineering Science at Osaka University (2009-) and Distinguished Professor of Osaka University (2013-). He is also visiting Director (2014-) (group leader: 2002-2013) of Hiroshi Ishiguro Laboratories at the Advanced Telecommunications Research Institute and the ATR fellow. His research interests include sensor networks, interactive robotics, and android science.

In 2011, he won the Osaka Cultural Award presented by the Osaka Prefectural Government and the Osaka City Government

ATR Fellow (2010-)

1. H. Sumioka, A. Nakae, R. Kanai and H. Ishiguro. Huggable communication medium decreases cortisol levels. Scientific Reports. 3034, pp. 1-6, 2013.

2. M. Alimardani, S. Nishio and H. Ishiguro. Humanlike robot hands controlled by brain activity arouse illusion of ownership in operators. Scientific Reports, 3(2396), 2013.

6. T. Kanda and H. Ishiguro. Human-robot interaction in social robotics. CRC Press, 2012.

13. H. Ishiguro, T. Minato, Y. Yoshikawa and M. Asada. Humanoid platform for cognitive developmental robotics. International Journal of Humanoid Robotics, 8(3), pp. 391-418, 2011.

43. H. Ishiguro. Scientific issues concerning androids. International Journal of Robotics Research, 26(1), pp. 105-117, 2007.

45. H. Ishiguro. Interactive Humanoids and Andoroids: Promise and Reality, Proceedings of the IEEE, 95 (4), pp. 699, 2007.

46. H. Ishiguro. Android Science: Conscious and subconscious recognition. Connection Science, 18(4), pp. 319-332, 2006.

Dr. Masatoshi Takeichi completed the B. Sc. and M. S. programs in biology at Nagoya University before receiving a doctorate in biophysics from Kyoto University in 1973. After attaining his Ph.D., Dr. Takeichi took a research fellowship at the Carnegie Institute Department of Embryology under Dr. Richard Pagano. He then returned to Kyoto University, attaining a full professorship in the Department of Biophysics (1986-1999), before becoming professor in the Department of Cell and Developmental Biology in the Graduate School of Biostudies at the same university. He assumed his current positions at the CDB in 2000.

Asahi Award, The Asahi Shimbun Company, 1994

Uehara Prize, 1996

Japan Academy Prize, 1996

Membership of the Japan Academy, 2000

Ross Harrison Prize (International Society of Developmental Biologists), 2001

Keio Medical Science Prize, 2001

Foreign honorary member of American Academy of Arts & Sciences, 2004

Person of Cultural Merits, 2004

Japan Prize, 2005

Foreign associate of the National Academy of Sciences, 2007

Associate member of EMBO, 2009

Thomson Reuters Citation Laureate, 2012

(1) Takeichi, M. (1977) Functional correlation between cell adhesive properties and some cell surface proteins. J. Cell Biol. 75, 464-474.

(2) Yoshida, N. and Takeichi, M. (1982) Teratocarcinoma cell adhesion: Identification of a cell surface protein involved in calcium-dependent cell aggregation. Cell 28, 217-224.

(3) Yoshida-Noro, C., Suzuki, N. and Takeichi, M. (1984) Molecular nature of the calcium-dependent cell-cell adhesion system in mouse teratocarcinoma and embryonic cells studied with a monoclonal antibody. Develop. Biol. 101, 19-27.

(4) Hatta, K. and Takeichi, M. (1986) Expression of N-cadherin adhesion molecules associated with early morphogenetic events in chicken embryos. Nature 320, 447-449.

(5) Shirayoshi, Y., Hatta, K., Hosoda, M., Tsunasawa, S., Sakiyama, F. and Takeichi, M. (1986) Cadherin cell adhesion molecules with distinct binding specificities share a common structure. EMBO J. 5, 2485-2488.

(6) Nagafuchi, A., Shirayoshi, Y., Okazaki, K., Yasuda, K. and Takeichi, M. (1987) Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA. Nature 329, 341-343.

(7) Nose, A., Nagafuchi, A. and Takeichi, M. (1988) Expressed recombinant cadherins mediate cell sorting in model systems. Cell 54, 993-1001.

(8) Hirano, S., Kimoto, N., Shimoyama, Y., Hirohashi, S. and Takeichi, M. (1992) Identification of a neural-catenin as a key regulator of cadherin function and multicellular organization. Cell 70, 293-301.

(9) Oda, H., Uemura, T., Harada, Y., Iwai, Y. and Takeichi, M. (1994) A Drosophila homolog of cadherin associated with Armadillo and essential for embryonic cell-cell adhesion. Develop. Biol., 165, 716-726.

(10) Uchida, N., Honjo, Y., Johnson, K.R., Wheelock, M.J. and Takeichi, M. (1996) The catenin/cadherin adhesion system is localized in synaptic junctions, bordering the active zone. J. Cell Biol. 135, 767-779.

(11) Usui, T., Shima, Y., Shimada, Y., Hirano, S., Burgess, R.W., Schwarz, T.L., Takeichi, M., and Uemura, T. (1999) Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled. Cell 98, 585-595.

(12) Abe, K., Chisaka, O., van Roy, F., and Takeichi, M. (2004) Stability of dendritic spines and synaptic contacts is controlled by N-catenin. Nature Neuroscience 7, 357-363

(13) Meng, W., Mushika, Y., Ichii, T., and Takeichi, M. (2008) Anchorage of microtubule minus-ends to adherens junctions regulates epithelial cell-cell contacts. Cell 135, 948-959

(14) Nishimura, Y., Honda, and Takeichi. M. (2012) Planar cell polarity links axes of spatial dynamics in neural tube closure. Cell 25, 1084-1097.

Evans is known for his work on nuclear receptors and the mechanism of hormone signaling. His cloning of the genes encoding the receptors for steroid, retinoid and thyroid hormones, revealed the evolutionary conservation of all nuclear hormone receptors. These hormone-receptor combinations help to control sugar, salt, calcium and fat metabolism as well as reproductive physiology. In addition, these receptors are primary targets in the treatment of breast cancer, prostate cancer and leukemia, as well as osteoporosis, inflammation and asthma.

Evans’ initial isolation of steroid receptors led to the surprising discovery of a class of related proteins termed ‘orphan receptors’ whose characterization revealed the existence of previously unknown signaling pathways for cholesterol, bile acids and fatty acids, fundamentally changing our views of both physiology and the treatment of disease.

Evans is a Professor in the Gene Expression Laboratory at the Salk Institute for Biological Studies, a Howard Hughes Medical Institute Investigator, and holds the March of Dimes Chair in Developmental and Molecular Biology at the Salk Institute. He is the recipient of the Albert Lasker Award (2004), the Wolfe Prize, Israel (2012) and a Member of the National Academy of Sciences and the Institute of Medicine.

Honors and Awards:

2014　　 Honorary Degree, University of Groningen, Netherlands

2013　　 Distinguished Leader in Insulin Resistance Award, World Congress in Insulin Resistance, Diabetes & Cardiovascular Disease

2013　　 Inaugural Lifetime Achievement Award, Samuel Waxman Cancer Research Foundation

2013　　 Dale Medal, Society for Endocrinology, UK

2012　　 Wolf Prize in Medicine, Wolf Foundation, Israel

2011　　 The Ellison Medical Foundation – Senior Scholar in Aging

2011　　 Rolf Sammet Guest Professorship Award, Goethe University, Frankfurt

2010　　 Heart Failure Association of America Award

2009　　 Ernst Knobil Award, UTHSCH

2009　　 Honorary Degree, Albany Medical College

2009　　 Honorary Degree, Mt. Sinai School of Medicine

2008　　 Endocrine Regulation Prize, IPSEN Foundation

2007　　 Albany Medical Center Prize in Medicine and Biomedical Research

2006　　 Harvey Prize, Technion University, Israel

2006　　 BIOCOM Life Sciences Heritage Award

2006　　 Gairdner Foundation International Award

2005　　 “Grande Medaille d’Or” of the French Academy of Sciences

2005　　 Glen T. Seaborg Medal, UCLA

2004　　 Albert Lasker Basic Medical Research Awar

2004　　 Simon M. Shubitz Cancer Prize and Lectureship, The University of Chicago

2003　　 Institute of Medicine of the National Academies

2003　　 Keio Medical Science Prize

2003　　 General Motors Cancer Research Foundation Alfred P. Sloan Medal

2003　　 March of Dimes Prize in Developmental Biology

2002　　 City of Medicine Award, Duke University

2000　　 1st Bristol-Myers Squibb Award for Distinguished Achieve. in Metab. Research

1999　　 Fred Conrad Koch Award, The Endocrine Society

1997　　 Gerald Aurbach Memorial Award, Association for Bone & Mineral Research

1997　　 American Academy of Arts and Sciences, Fellow

1996　　 Morton Lecture and Award, Biochemical Society, Univ. of Liverpool

1994　　 Dickson Prize in Medicine 1994-95, University of Pittsburgh

1994　　 California Scientist of the Year, 1994, California Museum of Science and Industry and the California Museum Foundation

1994　　 Transatlantic Medal Society for Endocrinology

1993　　 Edwin B. Astwood Lectureship Award, The Endocrine Society

1993　　 Fellow, The American Academy of Microbiology

1993　　 Robert J. and Claire Pasarow Foundation Award for Cancer Research

1992　　 Osborne and Mendel Award, American Institute of Nutrition

1991　　 Rita Levi Montalcini Award, Fidia Research Foundation Neuroscience

1991　　 Gregory Pincus Memorial Award, Worcester Found. for Experimental Biology

1990　　 Eleventh C.P. Rhoads Memorial Award, American Assoc. for Cancer Research

1989　　 Van Meter/Rorer Pharmaceuticals Prize, American Thyroid Association

1989　　 National Academy of Sciences, Member

1988　　 The Louis S. Goodman and Alfred Gilman Award by the American Society for Pharmacology and Experimental Therapeutics

1988　　 Gregory Pincus Medal, Laurentian Society

1975-78　　 National Institutes of Health, Fellowship

1975　　 Cancer Research Comm. of California, Research Associate Fellowship

1974　　 University of California Alumni, Award for Academic Distinction

Keynote Address:

2013　　 11th Annual World Congress on Insulin Resistance, Diabetes & Cardiovascular Disease, Los Angeles

2013　　 XXI ISHR World Congress, International Society for Heart Research, San Diego

2012　　 UKC2012, US-Korea conference on Science, Technology and Entrepreneurship, Los Angeles

2011　　 NCI Staff Scientist/Staff Clinician Retreat Keynote, Bethesda, MD

2011　　 Yale University Program in Integrative Cell Signaling and Neurobiology of Metabolism Symposium, Yale University

2011　　 UCSD Chronobiology Symposium – From Cells to the Clinic, San Diego, CA

2010　　 Aurbach Distinguished Lecture

2010　　 Distinguished Visiting Professor, Johns Hopkins

2010　　 9th International Congress on the Future of Breast Cancer, La Jolla, CA

2010　　 Inaugural Herbert Carter Lecture, University of Illinois

2009　　 Commencement Address, Albany Medical College

2009　　 Commencement Address, SUNY Buffalo School of Med., Biomedical Sciences

2009　　 New Frontiers in Skeletal Research: Bone, Fat and Brain Connections, ASBMR

2009　　 Symposium on Cancer Research, MD Anderson Cancer Center

2008　　 Inaugural Endocrine Research Showcase, Rutgers University

2007　　 Inaugural John Mendelsohn Visiting Professor in Cancer Medicine

2006　　 American Thyroid Association

2006　　 4th Annual COPP Lecture, University of British Columbia

2006　　 FASEB Summer Research Conference on Retinoids

2005　　 Frontiers of Clinical Investigation Symposium

2004　　 UCLA Department of Medicine Div. of Endocrinology, Diabetes and Hypertension Diabetes Endocrinology Research Center (DERC)Gala

2004　　 3rd International Metabolic Diseases Drug Discovery World Summit

2004　　 Gordon Research Conference on Lipoprotein Metabolism

2002　　 2nd International Nuclear Receptor Meeting, Sumitomo Chemical Co. Ltd. and Osaka Pharmaceuticals Co. Ltd.

2002　　 21st Symposium in Molecular Biology, The Pennsylvania State University

2002　　 FASEB Summer Research Conference on Mechanisms of Liver Growth, Differentiation, and Molecular Pathogenesis of Hepatic Diseases

2002　　 XV Int’l. Ecdysone Workshop, Crete

2001　　 Stowers Institute for Medical Research, Inaugural Symposium

2001　　 American Heart Association, North American Vascular Biology Organization and the National Heart, Lung, and Blood Institute

1999　　 Keystone Symposia on Inflammatory Paradigms and the Vasculature

1998　　 Dorcas Cummings Memorial Lecture, Cold Spring Harbor Symp on Transcription

1998　　 Keystone Symposia on Molecular and Cellular Biology of Gene Therapy

1991　　 Third Annual Usha Mahajani Symposium on Molecular Medicin

Primary structure and expression of a functional human glucocorticoid receptor cDNA.
Hollenberg SM, Weinberger C, Ong ES, Cerelli G, Oro A, Lebo R, Thompson EB, Rosenfeld MG, Evans RM. Nature. 1985 Dec 19-1986 Jan 1;318(6047):635-41. PMID: 2867473

The c-erb-A gene encodes a thyroid hormone receptor. Weinberger C, Thompson CC, Ong ES, Lebo R, Gruol DJ, Evans RM. Nature. 1986 Dec 18-31;324(6098):641-6. PMID: 2879243

Identification of a receptor for the morphogen retinoic acid. Giguere V, Ong ES, Segui P, Evans RM. Nature. 1987 Dec 17-23;330(6149):624-9. PMID: 2825036

The steroid and thyroid hormone receptor superfamily. Evans RM. Science. 1988 May 13;240(4854):889-95. Review. PMID: 3283939.

Nuclear receptor that identifies a novel retinoic acid response pathway. Mangelsdorf DJ, Ong ES, Dyck JA, Evans RM. Nature. 1990 May 17;345(6272):224-9. PMID: 2159111

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor. Heyman RA, Mangelsdorf DJ, Dyck JA, Stein RB, Eichele G, Evans RM, Thaller C. Cell. 1992 68: 397-406, 1992 PMID: 1310260

Structural determinants of nuclear receptor assembly on DNA direct repeats. Rastinejad F, Perlmann T, Evans RM, Sigler PB. Nature. 1995 May 18;375(6528):203-11. PMID: 7746322

LXR, a nuclear receptor that defines a distinct retinoid response pathway. Willy PJ, Umesono K, Ong ES, Evans RM, Heyman RA, Mangelsdorf DJ. Genes Dev. 1995 May 1;9(9):1033-45. PMID: 7744246

15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM, Evans RM. Cell. 1995 Dec 1;83(5):803-12. PMID: 8521497

Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity.
Wang YX, Lee CH, Tiep S, Yu RT, Ham J, Kang H, Evans RM. Cell. 2003 Apr 18;113(2):159-70. PMID: 12705865

AMPK and PPARdelta agonists are exercise mimetics. Narkar VA, Downes M, Yu RT, Embler E, Wang YX, Banayo E, Mihaylova MM, Nelson MC, Zou Y, Juguilon H, Kang H, Shaw RJ, Evans RM. Cell. 2008 Aug 8;134(3):405-15. doi: 10.1016/j.cell.2008.06.051. Epub 2008 Jul 31. PMID: 1867480

Cryptochromes mediate rhythmic repression of the glucocorticoid receptor. Lamia KA, Papp SJ, Yu RT, Barish GD, Uhlenhaut NH, Jonker JW, Downes M, Evans RM. Nature. 2011 Dec 14;480(7378):552-6. doi: 10.1038/nature10700. PMID: 22170608

A PPARγ-FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis. Jonker JW, Suh JM, Atkins AR, Ahmadian M, Li P, Whyte J, He M, Juguilon H, Yin YQ, Phillips CT, Yu RT, Olefsky JM, Henry RR, Downes M, Evans RM. Nature. 2012 May 17;485(7398):391-4. doi: 10.1038/nature10998. PMID: 22522926

An internationally recognized authority on the genetic basis of human cancer, Dr. Robert A. Weinberg is a founding member of the Whitehead Institute for Biomedical Research and the Daniel K. Ludwig Professor for Cancer Research at the Massachusetts Institute of Technology (MIT). He is also the first Director of the Ludwig Cancer Center at MIT.

Over the past three decades, Dr. Weinberg has made breakthrough discoveries in the molecular and genetic roots of cancers. His lab discovered the first oncogene in 1982 and the first tumor suppressor gene in 1986. Most recently, Dr. Weinberg and his collogues were the first to define the genetic rules that must be followed in order for a normal human cell to be transformed into a human cancer cell.

Dr. Weinberg’s lab is primarily concerned with how oncogenes, their normal counterparts (proto-oncogenes), and tumor suppressor genes fit together in the complex circuitry that controls cell growth. His lab recently succeeded in creating the first genetically defined human cancer cells. Dr. Weinberg is particularly interested in applying this knowledge to improve the diagnosis and treatment of breast cancer. At present his lab seeks to understand how a malicious population of tumor cells, called cancer stem cells, develop their metastatic powers and what biological conditions are required to eliminate them.

Author or editor of six books and more than 400 articles, Dr. Weinberg is best known for his comprehensive cancer textbook, “The Biology of Cancer” 2nd edition. His other books, intended for a lay audience, are “One Renegade Cell”, “Racing to the Beginning of the Road: The Search for the Origin of Cancer” and “Genes and the Biology of Cancer,” co-authored with Dr. Harold E. Varmus, former Director of the National Institutes of Health.

Dr. Weinberg is an elected Member of the U.S. National Academy of Sciences and Fellow of the American Academy of Arts and Sciences. He is also a Member of the American Philosophical Society and the Institute of Medicine. He has received the National Medal of Science (1997), the Wolf Prize in Medicine (2007), the Otto Warburg Medal (2007), and the Breakthrough Prize in Life Sciences (2013).

Discover Magazine Scientist of the Year, 1982

Warren Triennial Prize, Massachusetts General Hospital, 1983

Robert Koch Medal, Robert Koch Foundation, Germany, 1983

Hammer Cancer Foundation Award, 1984

National Academy of Sciences, U. S. Steel Foundation Award in Molecular Biology, 1984

Bristol-Myers Award for Distinguished Achievement in Cancer Research, 1984

Ph.D., honoris causa, Northwestern University, Evanston, Illinois, 1984

Antonio Feltrinelli Prize, Academia Nazionale dei Lincei, Rome, 1984

Member, U.S. National Academy of Sciences, 1985

Sloan Prize, General Motors Cancer Research Foundation, 1987

Ph.D., honoris causa, State University of New York, Stony Brook, 1988

Sc.D., honoris causa, Mount Sinai School of Medicine, City University of New York, 1989

Gairdner Foundation International Awards for Achievements in Medical Science, 1992

Charles Rodolphe Brupbacher Prize, 1995

G.H.A. Clowes Memorial Award, American Association for Cancer Research, 1996

Max Delbrück Medal of the Max-Delbrück Center, Berlin, 1996

Robert J. and Claire Pasarow Foundation, 1997

U.S. National Medal of Science, 1997

Keio Medical Science Foundation Prize, 1997

Killian Faculty Achievement Award, 1999

The Order Pour le Mérite for Sciences and the Arts, Berlin, 1999

Institute of Medicine, 2000

Wolf Foundation Prize, 2004

Prince of Asturias Science Award, Spain 2004

American Association for Cancer Research Landon Prize, 2006

Warren Alpert Prize, Harvard Medical School, 2007

MD. honoris causa, University of Uppsala, Sweden, 2007

InBev-Baillet Latour Health Prize, 2008

Breast Cancer Research Foundation, Jill Rose Award, 2008

Ph.D. honoris causa, Université Paris Descartes, 2008

ScD. honoris causa, Tufts University, 2009

La Grande Medaille, Academie des Sciences, Institut de France, 2009

MD. honoris causa, Helsinki University, 2010

Breakthrough Prize for Biomedical Research, 2013

1. Shih, C., Shilo, B., Goldfarb, M.P., Dannenberg, A., and Weinberg, R.A. (1979) Passage of Phenotypes of Chemically Transformed Cells via Transfection of DNA and Chromatin. Proc. Nat’l. Acad. Sci., USA, 76: 5714-5718.

2. Shih, C., Padhy, L.C., Murray, M., and Weinberg, R.A. (1981) Transforming Genes of Carcinomas and Neuroblastomas Introduced into Mouse Fibroblasts. Nature, 290: 261-264.

3. Shih, C. and Weinberg, R.A. (1982) Isolation of a Transforming Sequence from a Human Bladder Carcinoma Cell Line. Cell, 29: 161-169.

4. Parada, L.F., Tabin, C.J., Shih, C., and Weinberg, R.A. (1982) Human EJ Bladder Carcinoma Oncogene is Homologue of Harvey Sarcoma Virus ras Gene. Nature, 297: 474-478.

5. Tabin, C.J., Bradley, S.M., Bargmann, C.I., Weinberg, R.A., Papageorge, A.G., Scolnick, E.M., Dhar, R., Lowy, D.R., and Chang, E.H. (1982) Mechanism of Activation of a Human Oncogene. Nature, 300: 143-149.

6. Land, H., Parada, L.F., and Weinberg, R.A. (1983) Tumorigenic Conversion of Primary Embryo Fibroblasts Requires at Least Two Cooperating Oncogenes. Nature, 304: 596-602.

7. Friend, S.H., Bernards, R., Rogelj, S., Weinberg, R.A., Rapaport, J.M., Albert, D.M., and Dryja, T.P. (1986) A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature, 323: 643-646.

8. Hahn, W.C., Counter, C.M., Lundberg, A.S., Beijersbergen, R.L., Brooks, M.W., and Weinberg, R.A. (1999) Creation of human tumor cells with defined genetic elements. Nature, 400:464-468.

9. Yang, J., Mani, S.A., Liu Donaher, J., Richardson, A., Ramaswamy, S., Gitelman, I., and Weinberg, R.A. (2004) Twist, a master regulator of morphogenesis plays an essential role in tumor metastasis. Cell, 117:927-939.

10. Mani, S.A., Guo, W., Liao, M.J., Eaton, E.N., Ayyanan, A., Zhou, A.Y., Brooks, M., Reinhardt, F., Zhang, C.C., Shipitsin, M., Campbell, L.L., Polyak, K., Brisken, C., Yang, J. and Weinberg, R.A. (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell, 133:704-715.

Education ;

Research and professional experience ;

Editorial Board;

1987　　 The Encouragement Award, Japan Biochemical Society (Tokyo)

1990　　 Erwin von Bälz Preis, Boehringer Ingelheim (Tokyo)

1992　　 The Mochida Memorial Award, Mochida Foundation (Tokyo)

1993　　 Nikkei BP Prize, Nikkei Press (Tokyo)

1994　　 Emil Adolf von Behring Prize, Philipps-Universität Marburg (Marburg, Germany)

1995　　 Robert Koch Award, Koch Foundation (Bonn, Germany)

1995　　 Osaka Science Prize, Osaka Science Technology Foundation (Osaka)

1996　　 Boehring-Kitasato Prize, Hoechst Japan, Ltd. (Tokyo)

1997　　 Le Prix Antoine Lacassagne, French Cancer League (Paris, France)

1997　　 Mellon Prize, University of Pittsburgh (Pittsburgh, USA)

1998　　 Asahi Prize, Asahi Press Foundation (Tokyo)

1998　　 Takamatsu Cancer Award, Princess Takamatsu Foundation (Tokyo)

1998　　 Uehara Prize, Uehara Foundation (Tokyo)

2000　　 Japan Academy Prize and Imperial Prize, Japan Academy (Tokyo)

2001　　 Person of Cultural Merit, Japanese Government (Tokyo)

2004　　 Cell Death Society Prize, International Cell Death Society (Dublin, Ireland)

2010　　 Associate, The Japan Academy (Tokyo)

2012　　 Honorary Doctorate, University of Zurich (Zurich, Switzerland)

2012　　 Tomizo Yoshida Award, Japanese Cancer Association (Tokyo)

2012　　 Debrecen Award, Debrecen University (Debrecen, Hungary)

2013　　 Kyoto University Shi-Shi Award, Kyoto Univesity (Kyoto)

2013　　 Keio Medical Science Prize, Keio University Medical Science Fund (Tokyo)

(1) Nagata, S., Taira, H., Hall, A., Johnsrud, L., Streuli, M., Ecsodi, J., Boll, W., Cantell, K. & Weissmann, C. Synthesis in E. coli of a polypeptide with human leukocyte interferon activity. Nature 284, 316-320, 1980.

(2) Nagata, S., Mantei, N. & Weissmann, C. The structure of one of the eight or more distinct chromosomal genes for human interferon-. Nature 287, 401-408, 1980.

(3) Nagata, S., Tsuchiya, M., Asano, S., Kaziro, Y., Yamazaki, T., Yamamoto, O., Hirata, Y., Kubota, N., Oheda, M., Nomura, H. & Ono, M. Molecular cloning and expression of cDNA for human granuloctye colony-stimulating factor. Nature 319, 415-418, 1986.

(4) Fukunaga, R., Ishizaka-Ikeda, E., Seto, Y. & Nagata, S. Expression cloning of a receptor for murine granulocyte colony-stimulating factor. Cell 61, 341-350, 1990.

(5) Itoh, N., Yonehara, S., Ishii, A., Yonehara, M., Mizushima, S., Sameshima, M., Hase, A., Seto, Y. & Nagata, S. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 66, 233-243, 1991.

(6) Watanabe-Fukunaga, R., Brannan, C.I., Copeland, N.G., Jenkins, N.A. & Nagata, S. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356, 314-317, 1992.

(7) Fukunaga, R., Ishizaka-Ikeda, E. & Nagata, S. Growth and differentiation signals mediated by two distinct regions in the cytoplasmic domain of G-CSF receptor. Cell 74, 1079-1087, 1993.

(8) Ogasawara, J., Watanabe-Fukunaga, R., Adachi, M., Matsuzawa, A., Kasugai, T., Kitamura, Y., Itoh, N., Suda, T. & Nagata, S. Lethal effect of the anti-Fas antibody in mice. Nature 364, 806-809, 1993.

(9) Suda, T., Takahashi, T., Golstein, P. & Nagata, S. Molecular cloning and expression of the Fas ligand: a novel member of the tumor necrosis factor family. Cell 75, 1169-1178, 1993.

(10) Takahashi, T., Tanaka, M., Brannan, C.I., Jenkins, N.A., Copeland, N.G., Suda, T. & Nagata, S. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 76, 969-976, 1994.

(11) Enari, M., Hug, H. & Nagata, S. Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature 375, 78-81, 1995.

(12) Nagata, S. & Golstein, P. The Fas death factor. Science 267, 1449-1456, 1995.

(13) Enari, M., Talanian, R.V., Wong, W.W. & Nagata, S. Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature 380, 723-726, 1996.

(14) Nagata, S. Apoptosis by death factor. Cell 88, 355-365, 1997.

(15) Enari, M., Sakahira, H., Yokoyama, H., Okawa, K., Iwamatsu, A. & Nagata, S. A caspase-activated DNase that degrades DNA during apoptosis and its inhibitor ICAD. Nature 391, 43-50, 1998.

(16) Sakahira, H., Enari, M. & Nagata, S. Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 391, 96-99, 1998.

(17) Kawane, K., Fukuyama, H., Kondoh, G., Takeda, J., Ohsawa, Y., Uchiyama, Y. & Nagata, S. Requirement of DNase II for definitive erythropoiesis in the mouse fetal liver. Science 292, 1546-1549, 2001.

(18) Hanayama, R., Tanaka, M., Miwa, K., Shinohara, A., Iwamatsu, A. & Nagata, S. Identification of a factor that links apoptotic cells to phagocytes. Nature 417, 182-187, 2002.

(19) Nishimoto, S., Kawane, K., Watanabe-Fukunaga, R., Fukuyama, H., Ohsawa, Y., Uchiyama, Y., Hashida, N., Ohguro, N., Tano, Y., Morimoto, T., Fukuda, Y. & Nagata, S. Nuclear cataract caused by a lack of DNA degradation in the mouse eye lens. Nature 424, 1071-1074, 2003.

(20) Hanayama, R., Tanaka, M., Miyasaka, K., Aozasa, K., Koike, M., Uchiyama, Y. & Nagata, S. Autoimmune disease and impaired uptake of apoptotic cells in germinal centers of MFG-E8-deficient mice. Science 304, 1147-1150, 2004.

(21) Yoshida, H., Kawane, K., Koike, M., Mori, Y., Uchiyama, Y. & Nagata, S. Phosphatidylserine- dependent engulfment by macrophages of nuclei from erythroid precursor cells. Nature 437, 754-758, 2005

(22) Kawane, K., Ohtani, M., Miwa, K., Kizawa, T., Kanbara, Y., Yoshioka, Y., Yoshikawa, H., and Nagata, S.: Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages. Nature 443, 998-1002, 2006

(23) Miyanishi, M., Tada, K., Koike, M., Uchiyama, Y., Kitamura, T., and Nagata, S.: Identification of Tim-4 as a phosphatidylserine receptor. Nature 450: 435-439, 2007

(24) Kitano, M., Nakaya, M., Nakamura, T., Nagata, S. & Matsuda, M.: Imaging of Rab5 activity identifies essential regulators for phagosome maturation. Nature 453: 241-245, 2008

(25) Okabe, Y., Sano, T. & Nagata, S.: Regulation of the innate immune response by threonine phosphatase of Eyes absent. Nature 460: 520-524, 2009

(26) Nagata, S., Hanayama, R. & Kawane, K.: Autoimmunity and the Clearance of Dead Cells. Cell 140: 619-630, 2010

(27) Suzuki, J., Umeda, M., Sims JP. & Nagata, S.: Calcium-dependent phospholipid scrambling by TMEM16F. Nature 468: 834-838, 2010

(28) Suzuki, J., Denning, DP., Imanishi, E., Horvitz, HR. & Nagata, S.: Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells. Science 341: 403-406, 2013

Education

Positions held

L’Oreal-UNESCO award for women in science 2014

Inaba, K; Metray, JP; Crowley, MT; Steinman, RM (1990) Dendritic cells pulsed with protein antigens in vitro can prime antigen-specific, MHC-restricted T cells in situ. J. Exp. Med. 172 (2): 631-640.

Inaba, K; Inaba, M; Romani, N; Aya, H; Deguchi, M; Ikehara, S; Muramatsu, S; Steinman, RM (1992) Generation of large numbers of dendritic cells from mouse bone-marrow cultures supplemented with granulocyte macrophage colony-stimulating factor. J. Exp. Med. 176 (6): 1693-1702.

Inaba, K; Witmer-Pack, M; Inaba, M; Hathcock, KS; Sakuta, H; Azuma, M; Yagita, H; Okumura, K; Linsley, PS; Ikehara, S; Muramatsu, S; Hodes, RJ; Steinman, RM (1994) The Tissue distribution of the B7-2 costimulator in mice – abundant expression of dendritic cells in situ and during maturation in vitro. J. Exp. Med. 180 (5): 1849-1860.

Inaba, K; Pack, M; Inaba, M; Sakuta, H; Isdell, F; Steinman, RM (1997) High levels of a major histocompatibility complex II self peptide complex on dendritic cells from the T cell areas of lymph nodes. J. Exp. Med. 186 (5): 665-672.

Inaba, K; Turley, S; Yamaide, F; Iyoda, T; Mahnke, K; Inaba, M; Pack, M; Subklewe, M; Sauter, B; Sheff, D; Albert, M; Bhardwaj, N; Mellman, I; Steinman, RM (1998) Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells. J. Exp. Med. 188 (11): 2163-2173.

Hawiger, D; Inaba, K; Dorsett, Y; Guo, M; Mahnke, K; Rivera, M; Ravetch, JV; Steinman, RM; Nussenzweig, MC (2001) Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J. Exp. Med. 194 (6): 769-779.

yoda, T; Shimoyama, S; Liu, K; Omatsu, Y; Akiyama, Y; Maeda, Y; Takahara, K; Steinman, RM; Inaba, K (2002) The CD8+ dendritic cell subset selectively endocytoses dying cells in culture and in vivo. J. Exp. Med. 195 (10): 1289-1302.

Yamazaki, S; Iyoda, T; Tarbell, K; Olson, K; Velinzon, K; Inaba, K; Steinman, RM (2003) Direct expansion of functional CD25+CD4+ regulatory T cells by antigen-processing dendritic cells. J. Exp. Med. 198 (2): 235-247.

Nagaoka, K; Takahara, K; Yoshida, H; Steinman, RM; Saitoh, S; Akashi-Takamura, S; Miyake, K; Kang, YS; Park, CG; Inaba, K (2005) Association of SIGNR1 with TLR4-MD-2 enhances signal transduction by recognition of LPS in gram-negative bacteria. Int. Immunol. 17 (7): 827-836.

Onai, N; Kurabayashi, K; Hosoi-Amaike, M; Inaba, K; Ohteki, T (2013) A clonogenic progenitor with prominent plasmacytoid dendritic cell developmental potential. Immunity, 38(5):943-957.

Inaba, K (2012) A tribute to Ralph M. Steinman. Int. Immunol. 24 (1): 1-3.

Education:

Positions Held:

2001　　 Inoue Prize for Science (Inoue Foundation of Science)

2001　　 The Hideyo Noguchi Memorial Award for Medical Sciences

2002　　 Osaka Science Prize (Osaka Science & Technology)

2003　　 Takeda Prize for Medical Science (Takeda Science Foundation)

2004　　 The Prize of Princess Takamatsu Cancer Research Fund

2004　　 Robert Koch Prize (Robert Koch Foundation, Germany)

2005　　 Medal with Purple Ribbon (Japanese Cabinet Office)

2006　　 Asahi Prize (Asahi Shinbun)

2006　　 2004-2005 “Hottest Researcher” (Thomson Scientific)

2006　　 William B. Coley Award for Distinguished Research in BasicImmunology (Cancer Research Institute, USA)

2007　　 Uehara Prize (Uehara Memorial Foundation)

2007　　 2005-2006 “Hottest Researcher” (Thomson Scientific)

2007　　 Imperial Prize and Japan Academy Prize (Japan Academy)

2007　　 Milstein Award (International Society for Interferon and Cytokine Research)

2007　　 Thomson Research Front Award (Thomson Scientific)

2009　　 National Academy of Sciences of USA, Foreign Associate

2009　　 Person of Cultural Merit (Japanese Government)

2010　　 Keio International Medical Science Prize (Keio University)

2010　　 Avery-Landsteiner Prize (German Society for Immunology)

2010　　 EMBO Associate Member

2010　　 The 2011 Canada Gairdner International Award

1)Hemmi, H., Takeuchi, O., Kawai, T., Kaisho, T., Sato, S., Sanjo, H., Matsumoto, M., Hoshino, K., Wagner, H., Takeda, K. and Akira, S. A Toll-like receptor recognizes bacterial DNA. Nature, 408:740-745, 2000

2)Yamamoto, M., Sato, S., Hemmi, H., Sanjo, H., Uematsu, S., Kaisho, T., Hoshino, K., Takeuchi, O., Kobayashi, M., Fujita, T., Takeda, K. and Akira, S. Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4. Nature. 420:324-329, 2002.

3)Yamamoto, M., Sato, S., Hemmi, H., Hoshino, K., Kaisho, T., Sanjo, H.,
Takeuchi, O., Sugiyama, M., Okabe, M., Takeda, K. and Akira, S. Role of
adaptor TRIF in the MyD88-independent Toll-like receptor signaling pathway.
Science 301:640-643, 2003.

4)Yamamoto, M., Yamazaki, S., Uematsu, S., Sato, S., Hemmi, H., Hoshino, K.,
Kaisho, T., Kuwata, H., Takeuchi, O., Takeshige, K., Saitoh, T., Yamaoka, S.,
Yamamoto, N., Yamamoto, S., Muta, T., Takeda, K. and Akira, S. Regulation
of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein
IkBzeta. Nature 430: 218-222, 2004.

5)Akira, S., Uematsu, S. and Takeuchi, O. Pathogen recognition and innate
immunity. Cell. 24: 783-801, 2006.

6)Kato, H., Takeuchi, O., Sato, S., Yoneyama, M., Yamamoto, M., Matsui, K.,
Uematsu, S., Jung, A., Kawai, T., Ishii, K.J., Yamaguchi, O., Otsu, K., Tsujimura,
T., Koh, C.S., Reis e Sousa, C., Matsuura, Y., Fujita, T. and Akira, S.
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses.
Nature. 441: 101-105, 2006.

7)Saitoh T, Fujita N, Jang MH, Uematsu S, Yang BG, Satoh T, Omori H, Noda T,
Yamamoto N, Komatsu M, Tanaka K, Kawai T, Tsujimura T, Takeuchi O,
Yoshimori T, Akira S.
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta
production. Nature. ;456:264-268, 2008

8)Ishii KJ, Kawagoe T, Koyama S, Matsui K, Kumar H, Kawai T, Uematsu S,
Takeuchi O, Takeshita F, Coban C, Akira S.
TANK-binding kinase-1 delineates innate and adaptive immune responses to
DNA vaccines. Nature.451:725-729, 2008.

9)Matsushita K, Takeuchi O, Standley DM, Kumagai Y, Kawagoe T, Miyake T,
Satoh T, Kato H, Tsujimura T, Nakamura H, Akira S.
Zc3h12a is an RNase essential for controlling immune responses by regulating
mRNA decay.
Nature. 458:1185-1190, 2009.

10)Satoh T, Takeuchi O, Vandenbon A, Yasuda K, Tanaka Y, Kumagai Y,
Miyake T, Matsushita K, Okazaki T, Saitoh T, Honma K, Matsuyama T, Yui K,
Tsujimura T, Standley DM, Nakanishi K, Nakai K, Akira S.
The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses
against helminth infection.
Nat Immunol. 11:936-944, 2010.

11)Iwasaki H, Takeuchi O, Teraguchi S, Matsushita K, Uehata T, Kuniyoshi K, Satoh T, Saitoh T, Matsushita M, Standley DM, Akira S.
The IκB kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR-IL-1R by controlling degradation of regnase-1.
Nat Immunol. 12:1167-1175, 2011.

12)Satoh T, Kidoya H, Naito H, Yamamoto M, Takemura N, Nakagawa K, Yoshioka Y, Morii E, Takakura N, Takeuchi O, Akira S.
Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages.
Nature. 495:524-528, 2013.

13)Misawa T, Takahama M, Kozaki T, LeeH, Zou J, Saitoh T, Akira S.
Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome.
Nat Immunol. 14:454-460, 2013.

14)Uehata T, Iwasaki H, Vandenbon A, Matsushita K, Hernandez-Cuellar E, Kuniyoshi K, Satoh T, Mino T, Suzuki Y, Standley DM, Tsujimura T, Rakugi H, Isaka Y, Takeuchi O, Akira, S.
Malt1-induced cleavage of regnase-1 in CD4(+) helper T cells regulates immune activation.
Cell. 153:1036-1049, 2013.

15)Akira S.
Regnase-1, a Ribonuclease Involved in the Regulation of Immune Responses.
Cold Spring Harb Symp Quant Biol. (in press)

1992　　 Tsukahara Prize, Brain Science Foundation.

2000　　 Uehara Memorial Prize, Uehara Memorial Foundation.

2000　　 Tokizane Prize, Tokizane Memorial Foundation.

2003　　 Keio Medical Science Prize, Keio Medical Science Foundation.

2004　　 Asahi Prize, Asahi Cultural Foundation.

2004　　 Medal with Purple Ribbon, Cabinet Office, Government of Japan.

2007　　 Japan Academy Award, Japan Academy of Science

2014　　 Fujiwara Award

Hirabayashi, T., Takeuchi, D., Tamura, K., and Miyashita, Y. :
Microcircuits for hierarchical elaboration of object coding across primate temporal areas. Science 341, 191-195, 2013.

Miyamoto, K., Osada, T., Adachi, Y., Matsui, T., Kimura, H.M., and Miyashita, Y.:
Functional differentiation of memory retrieval network in macaque posterior parietal cortex. Neuron 77, 787-799, 2013.

Hirabayashi, T., Takeuchi, D. and Tamura, K. and Miyashita, Y. :
Functional microcircuit recruited during retrieval of object association memory in monkey perirhinal cortex. Neuron 77, 192-203, 2013.

Takeuchi, D., Hirabayashi, T., Tamura, K., and Miyashita, Y. :
Reversal of interlaminar signal between sensory and memory processing in monkey temporal cortex. Science 331, 1443-1447, 2011.

Kamigaki, T., Fukushima, T., and Miyashita,Y. :
Cognitive set reconfiguration signaled by macaque posterior parietal neurons. Neuron 61, 941-951, 2009.

Matsui, T., Koyano, K.W., Koyama, M., Nakahara, K., Takeda, T., Ohashi, Y., Naya, Y. and Miyashita, Y. :
MRI-based localization of electrophysiological recording sites within the cerebral cortex at single-voxel accuracy. Nature methods 4, 161-168, 2007.

Takeda, M., Naya, Y., Fujimichi, R., Takeuchi, D. and Miyashita, Y. :
Active maintenance of associative mnemonic signal in monkey inferior temporal cortex.
Neuron 48, 839-848, 2005.

Miyashita, Y. :
Cognitive memory: cellular and network machineries and their top-down control.
Science 306, 435-440, 2004.

Koyama, M., Hasegawa, I., Osada, T., Adachi, Y., Nakahara, K. and Miyashita, Y. :
Functional magnetic resonance imaging of macaque monkeys performing visually guided saccade tasks: comparison of cortical eye fields with humans. Neuron 41, 795-807, 2004.

Ohbayashi, M., Ohki, K. and Miyashita, Y. :
Conversion of working memory to motor sequence in the monkey premotor cortex.
Science 301, 233-236, 2003.

Kikyo, H., Ohki, K. and Miyashita, Y. :
Neural correlates for “feeling-of-knowing”: an fMRI parametric analysis.
Neuron 36, 177-186, 2002.

Nakahara, K., Hayashi, T., Konishi, S. and Miyashita, Y. :
Functional MRI of macaque monkeys performing a cognitive set-shifting task.
Science 295, 1532-1536, 2002.

Naya, Y., Yoshida, M.and Miyashita, Y. :
Backward spreading of memory retrieval signal in the primate temporal cortex.
Science 291, 661-664, 2001.

Tokuyama,W., Okuno,H., Hashimoto, T., Li, Y.X. and Miyashita, Y. :
BDNF upregulation during declarative memory formation in monkey inferior temporal cortex. Nature neuroscience 3, 1134-1142, 2000.

Tomita, H., Ohbayashi, M., Nakahara, K., Hasegawa, I. and Miyashita, Y. :
Top-down signal originating from the prefrontal cortex for memory retrieval.
Nature 401,699-703, 1999.

Hasegawa, I., Fukushima, T., Ihara, T. and Miyashita, Y. :
Callosal window between prefrontal cortices : cognitive interaction to retrieve long-term memory. Science 281, 814-818, 1998.

Konishi, S., Nakajima, K., Uchida, I., Kameyama, M., Nakahara, K., Sekihara K. and Miyashita, Y. :
Transient activation of inferior prefrontal cortex during cognitive set shifting.
Nature neuroscience 1, 80-84, 1998.

Sakai, K. and Miyashita, Y. :
Neural organization for the long-term memory of paired associates.
Nature 354, 152-155, 1991.

Miyashita, Y. :
Neuronal correlate of visual associative long-term memory in the primate temporal cortex. Nature 335, 817-820, 1988.

Miyashita, Y. and Chang, H.S. :
Neuronal correlate of pictorial short-term memory in the primate temporal cortex.
Nature 331, 68-70, 1988.

Education:

Academic Appointments:

Research Activities and Memberships

1989　　 7th Osaka Science Award

1990　　 4th Tsukahara Memorial Award (Brain Science Promotion Foundation)

1992　　 1st Matsubara Lecture Award (Gordon Conference)

1994　　 25th Naito Memorial Science Promotion Award (Naito Memorial Promotion Foundation)

1998　　 The Japan Academy Award, The Imperial Award

1999　　 Asahi Award (Asahi Newspaper Culture Foundation)

2010　　 The US Genomic Award for Outstanding Investigator in the Field of Single Molecule Fluorescence Microscopy

2011　　 Fellow of the US Biophysical Society

2013　　 Peson of Cultural merit

1.K. Fujita, M. Iwaki, A. H. Iwane, L. Marcucci, T. Yanagida “Switching of myosin-V motion between the lever-arm swing and Brownian search-and-catch”
Nat. Commun.,3:956 (2012)

2.S. Nishikawa, I. Arimoto, K. Ikezaki, M. Sugawa, H. Ueno, T. Komori, A. H Iwane, T. Yanagida. Switch between large hand-over-hand and small inchworm-like steps in myosin VI
Cell 142(6),879-88 (2010)

3.T. Fujii, A. H. Iwane, T. Yanagida, K. Namba. Direct visualization of secondary structures of F-actin by electron cryomicroscopy.
Nature 467(7316),724-8 (2010)

4.M. Iwaki, A. H. Iwane, T. Shimokawa, R. Cooke, T. Yanagida. Brownian search-and-catch mechanism for myosin-VI steps.
Nature Chem. Biol., 5(6), 403-405 (2009)

5.M. Nishikawa, H. Takagi, T. Shibata, A. H. Iwane, T. Yanagida, _Fluctuation Analysis of Mechanochemical Coupling Depending on the Type of Biomolecular Motors.
Phys. Rev. Lett., 101(12), 128103 (2008)

6.Y. Komori, A. Iwane and T.Yanagida: Myosin-V makes two Brownian 90o rotations per 36 nm step.
Nature Str. Mol. Biol. 14（10）:968-973 (2007)

7.J. Kozuka, H. Yokota, Y. Arai, Y. Ishii, T. Yanagida, _Dynamic polymorphism of single actin molecules in the actin filament.
Nature Chem. Biology, 2, 83-86 (2006)

8.Y. Taniguchi, M. Nishiyama, Y. Ishii, T. Yanagida. Entropy rectifies the Brownian steps of kinesin.
Nature Chem. Biol., 1, 346-351 (2005)

9.M. Nishiyama, H. Higuchi, T. Yanagida, _Chemomechanical coupling of the ATPase cycle to the forward and backward movements of single kinesin molecules.
Nature Cell Biology, 4, 790-797 (2002)

10.H. Tanaka, K. Homma, A. H. Iwane, E. Katayama, R. Ikebe, J. Saito, T. Yanagida and M. Ikebe: The motor domain determines the large step of myosin-V.
Nature 415, 192-195 (2002)

11.M. Nishiyama, E. Muto, Y. Inoue, T. Yanagida, H. Higuchi, _Substeps within the 8-nm step of the ATPase cycle of single kinesin molecules.
Nature Cell Biology, 3, 425-428 (2001)

12.M. Ueda, Y. Sako, T. Tanaka, P. Devreotes and T. Yanagida: Single molecule analysis of chemotactic signaling in Dictyostelium cells.
Science 294, 864-867 (2001)

13.Y. Sako, S. Minoguchi and T. Yanagida: Single-molecule imaging of EGFR signaling on the surface of living cells.
Nature Cell Biology 2, 168-172 (2000)

14.Y. Sambongi , Y. Iko, M. Tanabe, H. Omote, A. Iwamoto-Kihara, I. Ueda, T. Yanagida, Y. Wada and M. Futai: Mechanical Rotation of the c Subunit Oligomer in the ATP Synthase (FoF1): Direct Observation.
Science. 286, 1722-1724 (1999)

15.K. Kitamura, M. Tokunaga, A. H. Iwane and T. Yanagida: A single myosin head moves along an actin filament with regular steps of ~5.3nm.
Nature. 397, 129-134 (1999)

16.A. Ishijima, H. Kojima, T. Funatsu, M. Tokunaga, H. Higuchi, H. Tanaka, T. Yanagida, Simultaneous observation of individual ATPase and mechanical events by a single myosin molecule during interaction with actin.
Cell, 92, 161-171 (1998)

17.H. Yokota, K. Saito, T. Yanagida, _Single molecule imaging of fluorescently-labeled proteins on metal by surface plasmons in aqueous solution.
Phys. Rev. Lett., 80(20), 4606-4609 (1998)

18.C. Shingyoji, H. Higuchi, M. Yoshimura, E. Katayama and T. Yanagida: Dynein arms are oscillating force generators.
Nature. 393, 711-714 (1998)

19.R. D. Vale, T. Funatsu, D. W. Pierce, L. Romberg, Y. Harada and T. Yanagida: Direct observation of single kinesin molecules moving along.
Nature. 380, 451-453 (1996)

20.T. Funatsu, Y. Harada, M. Tokunaga, K. Saito and T. Yanagida: Imaging of single fluorescent molecules and individual ATP turnovers by single myosin molecules in aqueous solution.
Nature. 374, 555-559 (1995)

21.A. Ishijima, T. Doi, K. Sakurada and T. Yanagida: Sub-piconewton force fluctuations of actomyosin in vitro.
Nature. 352, 301-306 (1991)

22.A. Kishino and T. Yanagida: Force measurements by micromanipulation of a single actin filament by glass needles.
Nature. 334, 74-76 (1988)

23.Y. Harada, A. Noguchi, A. Kishino and T. Yanagida: Sliding movement of single actin filaments on one-headed myosin filaments.
Nature. 326, 805-808 (1987)

24.T. Yanagida, T. Arata and F. Oosawa: Sliding distance of actin filament induced by a myosin crossbridge during one ATP hydrolysis cycle.
Nature. 316, 366-369 (1985)

25.T. Yanagida, M. Nakase, K. Nishiyama and F. Oosawa: Direct observation of motion of single F-actin filaments in the presence of myosin.
Nature. 307, 58-60 (1984)

他200編

Studies geography, Chinese and Japanese at Paris University (1959-1963), at the School of oriental languages, Paris (1960-1963, 1965-1967) and at Oxford University, Wadham College (1963-1964).
Diploma of Chinese of the School of oriental languages (1967).
Doctor in geography (PhD, 1969, Paris University); thesis : Commercial hierarchies in Landes department, unpublished.
State doctor in letters (professoral dissertation, 1977, Paris IV University), thesis: Colonisation and cultural change in Hokkaidô, a study in cultural geography, microfilm, Paris, Publications orientalistes de France.
Military service at the Geographical Service of the French Army at Joigny and Baden-Baden (1964-1965).
Assistant lecturer at the School of Fine Art in Paris, 1967-1969.
Since 1969, numerous stays in Japan, totaling more than 17 years.
Teaches French at the Athénée français, Tokyo, 1969-1970, at the French-Japanese Institute, 1970.
Lector in French at Hokkaido University, 1970-1974.
Researcher at the Maison franco-japonaise, Tokyo, and invited researcher at Tohoku University, Sendai, 1975-1977.
Researcher at the CNRS (National Centre for Scientific Research), 1977-1979.
Since 1979 up to the present, director of studies at the EHESS, where he has directed the Centre for research on contemporary Japan from 1981 to 1999.
Detached as Director of the Maison　franco-japonaise in Tokyo, 1984-1988.
Detached as Professor at Miyagi University, Sendai, 1999-2001.
Detached as invited researcher at the Nichibunken (Centre for international research on Japanese culture, Kyoto), 1993-1994 and 2005-2006.
Retired since Sept. 1st, 2011.

*Lauréat de la Société de géographie pour Médiance, 1991/Prize of the French Geographical Society for his book Médiance, 1991 ;

*chevalier de l’Ordre du Mérite (ministère de l’Environnement), 1991/Chevalier of the Order of Merit (Ministry of Environment), 1991 ;

*élu membre de l’Academia europaea, 1991/Member of the Academia europaea, 1991 ;

*prix de la création culturelle japonaise 日本文化デザイン賞, 1995, pour ses travaux en théorie du paysage/Prize of the Japanese society for cultural design, for his works in the theory of landscape, 1995 ;

*prix Yamagata Bantô　山形蟠桃賞, 1997, pour ses travaux en japonologie/ Yamagata Bantô Prize for his works in Japanese studies, 1997 ;

*médaille d’argent du CNRS, 2000, pour ses travaux en géographie/Silver medal of the CNRS for his works in geography, 2000 ;

*prix culturel de la Société des architectes du Japon 日本建築学会文化賞, 2006, pour ses travaux sur l’habitat au Japon/Cultural prize of the Japanese society of architects, for his works on human settlements in Japan, 2006 ;

*Grand Prix de Fukuoka pour les cultures d’Asie 福岡アジア文化大賞 2009 [ce Grand Prix n’avait jusque-là jamais été décerné à un occidental] / Fukuoka Asian Culture Grand Prize, 2009 [this Grand Prize had until then never been awarded to a Westerner] ;

*Prix de la Fondation du Japon pour les études japonaises　国際交流基金賞, 2011 / Japan Foundation Award for Japanese studies, 2011 ;

*Membre d’honneur de la Société européenne des études japonaises, 2011 / Honorary member of the European Society for Japanese Studies, 2011 ;

*Prix des études japonaises (日本研究功労賞) 2012 des Instituts nationaux pour les humanités 人間文化研究機構/ NIHU Prize in Japanese studies 2012 ;

*Docteur honoris causa de l’Université Kwansei Gakuin (Japon, 1996) et de l’Université Laval (Québec, 2013) / Doctor Honoris causa, Kwansei Gakuin University (Japan, 1996) and Laval University(Quebec, 2013) ;

1. Le Japon, gestion de l’espace et changement social, Paris, Flammarion, 1976, 340 p. [Territorial policies and social change in Japan].

2. La Rizière et la banquise, colonisation et changement culturel à Hokkaidô, Paris, Publications orientalistes de France, 1980, 272 p. [Ricefield and icefield. Colonization and cultural change in Hokkaidô].

3. Vivre l’espace au Japon, Paris, Presses universitaires de France, 1982, 222 p. [A Phenomenology of space in Japan].　日本語訳『空間の日本文化』、筑摩書房、1985．

4. Le Sauvage et l’artifice, les Japonais devant la nature, Paris, Gallimard, 1997 (1ère éd. 1986), 314 p. Translated as Nature, artifice and Japanese culture, Pilkington, 1997.　『風土の日本. 自然と文化の通態』、筑摩書房、1988.

5. (direction/ed.) Le Japon et son double, logiques d’un autoportrait, Paris, Masson, 1987, 165 p. [The Logics of Japan’s self-portrait].

6. (direction/ed.) La Qualité de la ville : urbanité française, urbanité nippone, Tokyo, Maison franco-japonaise, 1987, 327 p. [The Quality of the city : French and Japanese urbanity].

7. Médiance, de milieux en paysages, Paris, Belin/Reclus, 2000 (1ère éd. 1990), 161 p. [Mediance : from milieu to landscape].　日本語訳『風土としての地球』、筑摩書房、1993.

8. 『日本の風景、西洋の景観、そして造景の時代』Nihon no fûkei, Seiô no keikan, soshite zôkei no jidai　 (Le Paysage au Japon, en Europe, et à l’ère du paysagement), Tokyo, Kodansha, 1990, 190 p. [Landscape in Japan and in Europe].

9. Du Geste à la cité, formes urbaines et lien social au Japon, Paris, Gallimard, 1993, 247 p. 日本語訳『都市の日本』、筑摩書房、1995 . Translated as Japan : cities and social bonds, Pilkington, 1997.

10. 『都市のコスモロジー』 Toshi no kosumorojî, Nichi-Bei-Ou toshi hikaku (Cosmologie de la ville, comparaison des villes du Japon, des Etats-Unis et d’Europe), Tokyo, Kodansha, 1993, 236 p. [Comparing urbanity in Japan, Europe and North America].

11. (direction/ed.) Cinq propositions pour une théorie du paysage, Seyssel, Champ Vallon, 1994, 125 p. [Five proposals for landscape].

12. (direction/ed.) La Maîtrise de la ville : urbanité française, urbanité nippone, II, Paris, Éditions de l’EHESS, 1994, 595 p. [Mastering the city : French and Japanese urbanity, II].

13. (direction/ed.) Dictionnaire de la civilisation japonaise, Paris, Hazan, 1994, 537 p. in quarto. [Dictionary of the Japanese civilization].

14. Les Raisons du paysage, de la Chine antique aux environnements de synthèse, Paris, Hazan, 1995, 192 p. [The Reasons of landscape, from ancient China to synthetic environments].

15. 『日本の風土性』Nihon no fûdosei (La Médiance nippone), Tokyo, NHK Ningen Daigaku, 1995, 130 p. et 2 vidéo-cassettes (total 6 h) [Japanese mediance].

16. Être humains sur la Terre, principes d’éthique de l’écoumène, Paris, Gallimard, 1996, 212 p.　日本語訳『地球と存在の哲学』、筑摩書房、1995 [Being human on the earth : principles of ecumenal ethics].

17. (direction/ed., avec/with Philippe Nys) Logique du lieu et œuvre humaine, Bruxelles, Ousia, 1997, 276 p. [Logic of place and human work].

18. (avec/with Maurice Sauzet et/and Jean-Paul Ferrier) De Japon en Méditerranée, architecture et présence au monde, Paris, Massin, 1999, 189 p. [From Japan to the Mediterranean : architecture and presence in the world].

19. (direction/ed.) La Mouvance : du jardin au territoire, cinquante mots pour le paysage, Paris, Éditions de la Villette, 1999, 100 p. [Fifty words for landscape].

20. (direction/ed.) Logique du lieu et dépassement de la modernité, tome I : Nishida, la mouvance philosophique, 390 p ; tome II : Du lieu nishidien vers d’autres mondes, 294 p., Bruxelles, Ousia, 2000. [Logic of place and the overcoming of modernity, I. Nishida and his influence, II. From the Nishidian place to other worlds].

21. Écoumène, introduction à l’étude des milieux humains, Paris, Belin, 2000, 271 p. [Ecumene : an introduction to the study of human milieux]. 日本語訳『風土学序説』、筑摩書房, 2002.

22. Les Déserts de Jean Verame, Milan/Paris, Skira/Seuil, 2000, 180 p. [Jean Verame’s deserts].

23. (対談集entretiens/talks)『都市、建築空間の場所生』Toshi, kenchiku kûkan to bashosei (Ville, architecture et sens du lieu), Sendai, Miyagi Daigaku, 2001, 331 p. [City, architecture, sense of place].

24. (avec/with Maurice SAUZET) Le Sens de l’espace au Japon. Vivre, penser, bâtir, Paris, Arguments, 2004, 227 p. [The Sense of space in Japan].

25. (direction/ed., avec/with Philippe BONNIN et/and Cynthia GHORRA-GOBIN) La Ville insoutenable, Paris, Belin, 2006, 366 p. [Unsustainable city].

26. (direction/ed.) Mouvance II. Du jardin au territoire, soixante-dix mots pour le paysage, Paris, Éditions de la Villette, 2006, 120 p. [Seventy words for landscape].

27. (編著direction/ed.)『日本の住まいに於ける風土性と持続性』 Nihon no sumai ni okeru fûdosei to jizokusei (Médiance et soutenabilité dans l’habitation japonaise), Kyôto, Nichibunken, 2007 [Mediance and sustainability in Japanese habitation].

28. La Pensée paysagère, Paris, Archibooks, 2008. 日本語訳『風景という知』、世界思想社、2010. Translated as Thinking through landscape, Routledge, 2013.

29. (direction/ed., avec/with Philippe BONNIN et/and Alessia DE BIASE) L’Habiter dans sa poétique première, Paris, Donner lieu, 2008, 404 p. [The primary poetics of inhabiting].

30. (direction/ed.) Une ville se refait-elle ? Paris, L’Harmattan, 2009, 142 p. (Géographie et cultures n° 65, printemps 2008) [ Can cities be remade ?].

31. (co-direction / co-editor) Être vers la vie / 生への存在. Ontologie, biologie, éthique de l’existence humaine. Actes du colloque de Cerisy-la-Salle, Ebisu n°40-41, automne 2008-été 2009, 224 p. [Being toward life. Ontology, biology, ethics of human existence. Proceedings of the Cerisy-la-Salle symposium].

32. Histoire de l’habitat idéal. De l’Orient vers l’Occident, Paris, Le Félin, 2010, 399 p. [History of the ideal abode : from East to West].

33. Milieu et identité humaine. Notes pour un dépassement de la modernité, Paris, Donner lieu, 2010, 150 p. [Milieu and human identity, being notes for an overcoming of modernity].

34. (Traduction et glose de) WATSUJI Tetsurô, Fûdo. Le milieu humain, Paris, Éditions du CNRS, 2011, 330 p. [和辻哲郎著『風土』の仏訳(Translation and gloss of) Fûdo. The human milieu].

35. (co-direction / co-editor) Donner lieu au monde : la poétique de l’habiter Paris, Donner lieu, 2012, 402 p.

36. (direction/ed.) De chose en fait : la question du milieu. Articles issus du colloque de Shin-Hirayu [From thing to fact : the question of milieu. Proceedings of the Shin-Hirayu symposium], Ebisu, n° 49 (printemps-été 2013), p. 50-113 .

1955.3　　 B.Sc. Faculty of Medicine, Kyoto University

1961.10-1963.9　　 Studied abroad at Dept. Psychiatry, University of Munich

1969.2-1970.10　　 visiting lecturer at Dept. Psychiatry, University of Heidelberg

1970.10-1974.12　　 Associate Professor, Faculty of Medicine, Nagoya City University

1974.12-1986.5　　 Full Professor, Faculty of Medicine, Nagoya City University

1986.5-1994.3　　 Full Professor, Faculty of Medicine, Kyoto University

1994.4-present　　 Advisor to President, Kyoto Hakuaikai Hospital

1994.4-present　　 Chief Scientist, Kawai Institute of Culture and Education(Director since 2008.4)

1994.4-1995.3　　 Full Professor, Faculty of Sociology, Ryukoku University

1995.4-2001.3　　 Full Professor, Faculty of Intercultural Communications, Ryukoku University

2002.5-present　　 Standing Director, Japanisch-Deutsches Kulturinstitut (President since 2013.5)

2004.4-2005.9　　 Visiting Professor, Faculty of Letters, Ritsumeikan University

1981　　 The 3rd Philipp Franz von Siebold Prize

1985　　 The 1st Margrit Egner Award

2003　　 The 15th Tetsuro Watsuji Prize for Culture

2010　　 The 64th Mainichi Cultural Award for Publications

2012　　 The 30th Kyoto Prefecture Cultural Award for Lifetime Achievements

35 single-authored books in total
For details of published books in Japanese, please refer to the Japanese web page.

1992　　 Écrits de Psychopathologie Phénoménologique (Presses Universitaires de France, Paris).

1995　　 Zwischen Mensch und Mensch. Strukturen japanischer Subjektivität ( Wissenschaftliche

2000　　 L’Entre. Une approche phénoménologique de la schizophrénie (Jérôme Millon, Grenoble).

2005　　 Scritti di psicopatologia fenomenologica (G. Fioriti, Roma).

2013　　 TRA per una fenomenologi dell’ incontro (Il Pozzo die Giacobbe, Roma).

19 translated books, 27 edited books,
47 papers in European languages (without co-author)
144 Japanese papers (without co-author), 14 Japanese papers (with co-authors)

Professor Alastair V Campbell is the Director, of the Centre for Biomedical Ethics in the Yong Loo Lin School of Medicine of the National University of Singapore. He is a former President of the International Association of Bioethics. He is a recipient of the HK Beecher Award, a Fellow of the Hastings Centre, New York and of the Ethox Centre, University of Oxford, Honorary Vice‐President of the Institute of Medical Ethics, and elected Corresponding Fellow of the Royal Society of Edinburgh. His recent books include Health as Liberation (1996), Medical Ethics (with D.G. Jones and G. Gillet, 3rd Edition 2005), The Body in Bioethics (2009) and Bioethics: the Basics (May, 2013). He was formerly chair of the Ethics and Governance Council of UK Biobank and currently a member of the Bioethics Advisory Committee to the Singapore Government and of the National Medical Ethics Committee of the Singapore Ministry of Health.

1) H.K. Beecher Award, Hastings Center, New York, 2000

2) Corresponding Fellow, Royal Society of Edinburgh, 2011

Books (or book chapters)

1) The Body in Bioethics, Routledge-Cavendish (February 2009)

2) Bioethics: the Basics (Routledge-Cavendish, 2013)

3) Campbell*, A V, Jacqueline J L CHIN* and T C VOO*, “Ethics and Attitudes”. In A Practical Guide for Medical
Teachers, 4 ed., 253. London: Elsevier, 2013. 413 pp.

4) Campbell, A V, “Why The Body Matters: reflections on John Harris’s Account of Organ Procurement”. In From
Theory to Practice in Bioethics: An Anthology Dedicated to the Works of John Harris. Manchester University Press, 2013.

Articles in referred journal

1) With Ang, A., Loke, P., Chong, S.A., Live or Let Die: Ethical Issues in a Psychiatric Patient with End-stage
Renal Failure Annals Academy of Medicine, Vol. 38 No. 4 pp. 370-373 (2009)

2) With SA Chong, Capps, B., Subramaniam, M., Voo, T.C Clinical Research in Time of Pandemics Public Health
Ethics,3(1): 35-38 (2010)

3) CHIN, Jacqueline J L and A V Campbell, “Transplant tourism or international transplant medicine? A case
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Professor Hisatake Kato is the President of Tottori University of Environmental Studies. He was born in Tokyo in 1937 and raised there. He studied philosophy at Tokyo University. From 1969 to 2001 he taught philosophy and ethics at Yamagata University, Tohoku University, Chiba University and Kyoto University. From 1982 to 1983 he was on sabbatical leave and stayed at Munich and Bochum for research.

He is the chair of the Philosophical Association of Japan from 1999 and a member of the steering committee of the Japan Association for Bioethics Studies from 1987. He is also a member of the steering committee of the International Study Center of Japanese Culture. He serves on various governmental councils such as Council for Science and Technology and Health Science Council.

He won the Yamazaki Prize for Philosophy in 1979 and the Watsuji Tetsuro Prize for Culture in 1994. He was awarded Medal with Purple Ribbon in 2000 for his contribution to philosophy and ethics.

He is the author of more than 20 books on philosophy and ethics in Japanese, including The Genesis and Principle of Hegel’s Philosophy (Miraisha, 1980), An Introduction to Bioethics (Miraisha, 1986), Philosophy of Jokes (Kodansha, 1987), Philosophy of Forms (Chuokoronsha, 1991), An Introduction to Environmental Ethics (Maruzen, 1991), Mission of Philosophy (Miraisha, 1992), Hegel’s Philosophy of Right (Seidosha, 1993), Ethica of 21 Century (Mraisha, 1993), Technology and Ethics (NHK Press, 1996), Brain Death, Clone, and Gene Therapy (PHP Press, 1999), Ethics of Parenting (Maruzen, 2000), View of Value and Science/Technology (Iwanami, 2001).

Shimizu T, The Ethics of Unity and Difference: Interpretations of Japanese Behaviour Surrounding 11 March 2011, Tetsuji Uehiro,ed. Ethics for the Future of Life: Proceedings of the 2012 Uehiro-Carnegie-Oxford Ethics Conference, The Oxford Uehiro Center for Practical Ethics, 2013: 134-143.

Shimizu T., Palliative Care, Encyclopedia of Applied Ethics, 2nd ed., vol.3: 328-337, Elsevier, 2012.2

Shimizu T. & Burnett C., eds., Words in medieval logic, theology and psychology. Brill, 2009

Shimizu T., Non-consequentialist Theory of Proportionality: with reference to the Ethical Controversy over Sedation in Terminal Stage, Journal of Philosophy and Ethics in Health Care and Medicine, 2 (2007): 4-25.

Shimizu T., “Word and Esse in Anselm and Abelard”，G.E.M.Gasper & H.Kohlenberger, eds., Anselm and Abelard: Investigations and Juxtapositions，pp.179-195，Pontifical Institute of Medieval Studies，2006．

Shimizu T., “The place of intellectus in the theory of signification by Abelard and ars meliduna”，Intellect et imagination dans la Philosophie Medievale: Actes du XIIe Congres International de Philosophie Medievale de la Societe Internationale pour l’Etude de la Philosophie Medievale( S.I.E.P.M.) Porto, du 26 au 31 aout 2002, pp.927-939，Brepols，2006．

Shimizu T.,”Words and Concepts in Anselm and Abelard”，J.Biard，ed.，Langage， sciences， philosophie au XIIe si`ecle，pp.177-197，Paris: Vrin，1999．

Shimizu T., “Alcuin’s Theory of Signification and System of Philosophy”， Didascalia 2，pp.1-18，(1996), 1998．

Shimizu T., “From Vocalism to Nominalism : Progression in Abaelard’s Theory of Signification”，Didascalia 1, pp.15-46, 1995．

Shimizu T., “Time and Eternity : Ockham’s Logical Point of View”，Franciscan Studies， 50(1990)，pp.283-307, 1993．

B.Sc. Dept. of Philosophy, Faculty of Letters, Kyoto University
Finished Ph.D. Course, Graduate School of Letters, Kyoto University
Studied abroad in France as a French Government Scholarship Recipient
Research Assistant Department of Philosophy, Collège de France
Lecturer, Faculty of Literature and Human Sciences, Osaka City University
Professor, Graduate School of Literature and Human Sciences, Osaka City University
Professor, Graduate School of Letters, Kyoto University
Presently, Professor of Faculty of Letters, Ryukoku University

The Tetsuro Watsuji Prize for Culture

Japan Academy Prize

La philosophie naturelle de Descartes(Paris, Vrin),

『デカルト哲学の体系ー自然学・形而上学・道徳論』（勁草書房）、

『科学哲学』（産業図書）、

『デカルトの自然哲学』 （岩波書店）、

『デカルト哲学とその射程』（弘文堂）、